If the uniqueness of these buildings is not sought, nor the number of inhabitants is prioritized, having this type of buildings is a detriment.
The buildings of Paris, London or Tokyo, as well as those specific to each region, do not have the ability to create Epic Projects, so you can not get with them the speed-up tokens, so necessary when you want to do, for example, the Contest of Mayors with some success.
That is why an interesting trick is NOT to create buildings of these types, and only create residential buildings, which can be improved with Epic Projects.